Monday, February 27, 2012

Association Mapping in Plants

Association (linkage disequilibrium [LD]) studies represent a novel powerful approach to evaluate candidate genes regulating plant phenotype and identify alleles of key interest at these genes. It is based on correlation between gene sequence and plant performance for target traits, and represent a powerful approach to evaluate candidate genes regulating the plant phenotype.

This new technique takes into account the thousands of genes to evaluate for QTL effect and is a more efficient approach that does not require generation of segregating populations/large numbers of progeny. As it can utilize all of the historic recombination events in a diverse population of individuals it can generate higher resolution genetic maps and, is needed to complement current map based cloning methods.

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